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06.142022
Tumor-induced erythroid precursor-differentiated myeloid cells mediate immunosuppression and curtail anti-PD-1/PD-L1 treatment efficacy
  • 06.142022
    Tumor-induced erythroid precursor-differentiated myeloid cells mediate immunosuppression and curtail anti-PD-1/PD-L1 treatment efficacy
    On the cover: The transdifferentiation paths of erythroid precursor cells (EPCs) under the influence of tumor is delineated from Palantir algorithm‐based single-cell transcriptomic trajectory analysis (Long et al., 674–693), and embedded in
  • 12.302021
    TCRCure Biopharma Ltd. Conducts Investigator Meeting in Preparation for New Cervical Cancer Drug Study for TC-E202 (1st IND approved PD-1 antibody armed TCR-T compound in the world)
    TCRCure Biopharma Ltd. Conducts Investigator Meeting in Preparation for New Cervical Cancer Drug Study for TC-E202 (1st IND approved PD-1 antibody armed TCR-T compound in the world)
  • 11.192021
    TCRCure Receives IND for Phase I/II TC-E202 Cervical Cancer Clinical Trial from NMPA
    19 November 2021. TCRCure have received Investigational New Drug (IND) approval from the CENTER FOR DRUG EVALUATION, NMPA (the “CDE”)for the Phase 1/2 clinical study of Modified autologous T cells for targeting HPV and delivery of anti-PD-1 in the treatment of HPV-positive recurrence and metastasis cervical cancer.
  • 06.122019
    GMP certified Guangdong manufacturing site construction launched
    TCRCure’s Guangdong manufacturing site, which includes GMP certified cell production facilities, office space, and labs for quality assurance, research and development, launched construction in Guangdong Medical Valley.
  • 06.042019
    New GMP manufacturing facility launched
    In May 2019, TCRCure opened a new research and manufacturing site in the Los Angeles bioscience corridor. The 5000 square foot facility includes 1400 s.f. of GMP-compliant manufacturing space and 1000 s.f. of R&D space, plus additional flex space. Patient cell therapy products will be produced in a 600 square foot ISO 7 cleanroom according to cGMPs for cell-therapy manufacturing. It will be TCRCure’s major site for clinical-grade therapeutic production in the US.
  • 11.022018
    TCRCure Chongqing Research Institute passes certification of quality, environmental, and occupational health and safety.
    TCRCure Chongqing Research Institute passes certification of quality, environmental, and occupational health and safety.
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