Highlights
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NK cells are safe in allogeneic applications and therefore are ideal off-the-shelf drugs.
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NK cell-based therapeutics have shown satisfying safety profiles and promising efficiency in cancer treatment.
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NK cells possess a reservoir of innate immune receptors targeting various types of cancer cells.
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With proper engineering, NK cells can function as the universal anti-cancer drugs that are not restricted to HLA and cancer types.
Breaking boundaries: Current progress of anticancer NK cell-based drug development - ScienceDirect