Advisory Team

Dr. Mark M. Davis is the Burt and Marion Avery Family Professor of Immunology at Stanford University. Dr. Davis has been an investigator at the Howard Hughes Medical Institute since 1987. He is also a member of National Academy of Sciences, American Academy of Arts and Sciences, and National Academy of Medicine. Since his ground-breaking cloning of T cell antigen receptor (TCR) genes in 1984, Dr. Davis has been a pioneer and leader the field of molecular immunology. Specifically, by pushing the boundaries of knowledge in multiple areas, such as antigen receptor recognition, thymic selection, and B cell terminal differentiation, his discoveries shaped our understanding of self versus non-self discrimination, the most fundamental question in adaptive immunity. In addition, the Davis lab is the acclaimed source of technology integration and innovation. The application of protein chemistry, biophysics and live cell imaging in Davis lab have made the study of T cell recognition the most advanced and quantitative of any system of cell-cell recognition in biology. Technologies developed in Davis lab, such as peptide-MHC tetramers, have become standard tools in basic and clinical immunology studies. In 2004, Dr. Davis became the founding director of Stanford Institute for Immunity, Transplantation and Infection and an advocate of human immunology. He then changed his lab’s focus away from basic immunology to studies of the human immune system. Here, he has also had a tremendous impact, developing more advanced ways to monitor immunity and responses clinically, and integrating repertoire sequencing, single cell genomics and proteomics technologies to challenge immunological dogma and the power of human work to contribute to basic immunological principals. His innovations and dedication have opened a new chapter in human immunology and translational medicine.

Professor Mark M. Davis
Director of Stanford Institute for Immunity, Transplantation and Infection
Member of the American Academy of Sciences, the American Academy of Sciences and Arts, American College of Medicine; and, Fellow, the Royal Society of the United Kingdom

 

 

Dr. Qi-Jing Li is a molecular immunologist at Duke University Medical Center. He was trained by Dr. Mark Davis at Stanford University, where he initiated his scientific career as a T cell biologist. Dr. Li’s early research focused on the sensitivity of the T cell antigen receptor (TCR). He made a series of contributions in determining the minimal subunit and rate-limiting step of TCR antigen recognition. His pioneer work introduced microRNA into the immunology field and determined that miR-181a was an intrinsic master regulator for T cell sensitivity. In 2008, Dr. Li started up his own lab at Duke, where he continued his research in the field of autoimmunity and tumor immunology. Taking microRNAs as tools for discovery and targets for immunomodulation, his work has been focused on regulatory mechanisms during T cell functional differentiation, as well as interplays between T cells and the tumor microenvironment. On the front of translational medicine, Dr. Li has been continuously establishing new technology platforms, engineering new cell therapy tools and developing them to the clinical stage for immunotherapy and immune monitoring. He has published more than 75 papers in high profile journals including Annual Reviews in Immunology, Cell, Nature, Nature Medicine, Nature Immunology, Nature Cell Biology, Nature Communications, Immunity, Journal of Clinical Investigation, Science Signaling, P.N.A.S, Blood, etc.

 

Professor Li has rich experience in cell immunotherapy and translational medicine. He has led or participated in multiple clinical trials in China and the US. As a scientific consultant, he was also involved in the foundation of Hrain Biotechnology in China, whose work demonstrated clinical excellence and received IND approval from CFDA.

Professor Qi-Jing Li
Chief Scientific Officer
Ph.D.
Associate Professor of Immunology
Duke University  
 

 

 

Professor Pin Wang is a leading scientist in the field of immune engineering and targeted gene/drug delivery. He has published more than 70 papers in top-tier journals including Nature Biotechnology, P.N.A.S, Nano Letter, ACS Nano, Gene Therapy, Human Gene Therapy, Molecular Therapy, J.A.C.S, Pharmaceutical Research, Vaccine, Biomaterials, Molecular Pharmaceutic. He has 4 patents under approval by USPTO. The DC targeting lentiviral vector developed in his team has entered Phase I clinical trial NCT02122861.

 

Professor Wang has long been engaged in translational research and is an entrepreneur dedicated to the industrialization of basic research. He has co-founded 3 biotech companies in the United States: Immune Design, EvoRx Technology, and Vali Nanomedical. Immune Design eventually entered IPO at NASDAQ and was acquired by Merck in 2018. Professor Wang was also involved the foundation of Hrain Biotechlonogy as a scientific consultant, whose work demonstrated clinical excellence and received IND approval from the CFDA. His team has profound experience in next generation cancer vaccines and CAR-T design, as well as high-performance viral product manufacturing.

Professor Pin Wang
Chief Technology Officer
Ph.D.
Zohrab A. Kaprielian Professor
University of Southern California

 

 

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